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Journal of Agricultural Chemistry and Biotechnology
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Azzaz, N., hamed, S., Mohamed, A. (2022). Antimicrobial and Anticancer Activities of Syzygium cumini Extracts. Journal of Agricultural Chemistry and Biotechnology, 13(3), 35-38. doi: 10.21608/jacb.2022.118330.1017
N. Azzaz; sahar elsaid hamed; Aml Mohamed. "Antimicrobial and Anticancer Activities of Syzygium cumini Extracts". Journal of Agricultural Chemistry and Biotechnology, 13, 3, 2022, 35-38. doi: 10.21608/jacb.2022.118330.1017
Azzaz, N., hamed, S., Mohamed, A. (2022). 'Antimicrobial and Anticancer Activities of Syzygium cumini Extracts', Journal of Agricultural Chemistry and Biotechnology, 13(3), pp. 35-38. doi: 10.21608/jacb.2022.118330.1017
Azzaz, N., hamed, S., Mohamed, A. Antimicrobial and Anticancer Activities of Syzygium cumini Extracts. Journal of Agricultural Chemistry and Biotechnology, 2022; 13(3): 35-38. doi: 10.21608/jacb.2022.118330.1017

Antimicrobial and Anticancer Activities of Syzygium cumini Extracts

Article 1, Volume 13, Issue 3, March 2022, Page 35-38  XML PDF (458.89 K)
Document Type: Original Article
DOI: 10.21608/jacb.2022.118330.1017
Authors
N. Azzaz1; sahar elsaid hamed email 2; Aml Mohamed1
1Dept. Chem., Fac. of Agric., Damietta University, Damietta
2agricultural chemistry Damitta university
Abstract
Syzygium cumini belongs to the family L. to Myrtaceae which are consumed as cherry-shaped fruits and are called pamposa in Egypt. The extracts of this fruit possess effective substances that haveantimicrobial, antioxidant and anti-cancer effects. The methanolic extracts of S. cumini fruit and seeds were tested on three types of human cancer cells, and also as anti-microbial substances on six microorganisms, three bacteria and three fungal strains. The methanolic extract of unripe fruit pulp has the strongest inhibition (82.2%) against DPPH radical using 25 μg/mL while methanolic extract of ripe fruits pulp gave lowest inhibition value of 28.02% at the same concentration. The results showed that the methanolic extract (0.1%) of the pulp of the ripe fruits was more effective on microbial strains and fungal strains. The methanolic extract of unripe fruit seeds of S. cumini was showed that the best anticancer activity was obtained using the high concentration of the tested samples (1000 μg/ml) against colorectal adenocarcinoma (Caco2) with an IC50 value was 30.93.
Keywords
Syzygium cumini; antimicrobial; colon; prostate; liver adenocarcinoma
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