ANTIFUNGAL EFFECT AND CYTOTOXIC AVTIVITY AGAINST HUMAN TUMORS OF SOME MEDICINAL PLANTS ADDED TO COOKIES FORMULA

Document Type : Original Article

Author

Food Technology Research Institute, Agricultural Research Center, Giza, Egypt.

Abstract

Three medicinal plants namely carob. tamarind, and doum were investigated for
their chemical composition, the most acceptable level added to cookies formula,
antifungal effect, and cytotoxic activity against human tumors cell lines. The most
acceptable level added to the cookies formula was 10% for each plant. The three
medicinal plant-extracts had an antifungal effect against the three tested fungi
Aspergillus parasiticus, A. ochraceus and Fu senium moniliform but the doum extract
had the strongest effect. Carob extract had cytotoxic activity against breast carcinoma
cell line (MCH7) but both tamarind and dourn had cytotoxic activity against breast
carcinoma cell line (MCH7) and human hep 3tO cellular carcinoma cell line (Hepg2).
These results sugges.t that carob, tamarind, end doum could be utilized as functional
foods or food ingredients.