ANTIMICROBIAL ACTIVITIES OF CERTAIN EGYPTIAN MEDICINAL PLANT EXTRACTS AND ESSENTIAL OILS

Document Type : Original Article

Authors

1 National Organization for Drug Control and Research (NODCAR)

2 Faculty of Science, Helwan University.

Abstract

Sixteen Egyptian medicinal plants namely Harmela ,Arghel, Chaste tree,
Egyptian acacia, Lemon grass, Fennel, Garden chrysanthemum, Oregano, Jojoba,
Common rue, Great plantein, Camel's hey, Ben-nut, Cypress, Juniper and Egyptian
Balsam were screened for their antimicrobial activity in vitro against six Gram -
positive bacteria [ Bacillus subtilis (CAIM1007), Bacillus p < /em>umilus (CAlM 1303),
Stap < /em>hylococcus aureus (CAlM 1352), Staphylococcus epidermidis (CAlM 1353),
Streptococcus sp. (CAlM 1221) and Micrococcus lutues (CAlM 1246) ] and seven
Gram negative - bacteria [ Escherichia coli (CAlM 1357), Pseudomonas fluorescens
(CAlM 1221), Salmonella typhimurium (CAlM 1350), Salmonella typhi, Salmonella
treforest, Shigella sp. (NMRO) and Bordetella bronchiseptica (ATCC 4617) ] as well
as two yeasts [( Candida albicans (CAlM 22) and Saccharomyces cerevisiae (CAlM
14)] and two fungal strains [ Aspergillus niger and Aspergillus flavus ]. The obtained
results indicated that the water extract of Oregano (Origanum vulgare) and Ben-nut
(Moringa peregrina) only gave highly antimicrobial activity, while the organic solvent
extracts (Ethanol and Petroleum ether) of Oregano, Juniper, Harmela, Arghel and
Camel's hey were found to possess moderate activities against different
microorganisms. Data also revealed that all oils have high activities in comparison
with other extracts and oil of (Origanum vulg.are) and (Moringa peregrina) were the
most effective against all the tested microorganisms.