Mohamed, M., Afifi, A. (2011). EFFECT OF SOME POLYUNSATURATED FATTY ACIDS RICH-OILS ON PLASMA LIPID PROFILES USING NORMAL RATS. Journal of Agricultural Chemistry and Biotechnology, 2(2), 49-59. doi: 10.21608/jacb.2011.56997
Magda S. Mohamed; Abeer A. Afifi. "EFFECT OF SOME POLYUNSATURATED FATTY ACIDS RICH-OILS ON PLASMA LIPID PROFILES USING NORMAL RATS". Journal of Agricultural Chemistry and Biotechnology, 2, 2, 2011, 49-59. doi: 10.21608/jacb.2011.56997
Mohamed, M., Afifi, A. (2011). 'EFFECT OF SOME POLYUNSATURATED FATTY ACIDS RICH-OILS ON PLASMA LIPID PROFILES USING NORMAL RATS', Journal of Agricultural Chemistry and Biotechnology, 2(2), pp. 49-59. doi: 10.21608/jacb.2011.56997
Mohamed, M., Afifi, A. EFFECT OF SOME POLYUNSATURATED FATTY ACIDS RICH-OILS ON PLASMA LIPID PROFILES USING NORMAL RATS. Journal of Agricultural Chemistry and Biotechnology, 2011; 2(2): 49-59. doi: 10.21608/jacb.2011.56997
EFFECT OF SOME POLYUNSATURATED FATTY ACIDS RICH-OILS ON PLASMA LIPID PROFILES USING NORMAL RATS
Food Sci. and Nutrition Dept., National Res. Center, Dokki, Cairo, Egypt.
Abstract
The purpose of this study was to examine whether using small amount (8%) of flaxseed oil and small amount of evening primrose oil (8%) may affect the level of blood lipid profiles in rats. Twenty one male albino ratswere divided randomly into three groups each of seven rats.One group received a basal diet as a control group; the other two groups were fed on diet with flaxseed oil (FO) or evening primrose oil (EPO). After 6 weeks, rats were fasted over night and blood samples were collected. The evolution of nutritional value depended on determination of total food intake, body weight gain and food efficiency ratio, the nutritional status of rats fed different diets was also evaluated through determination of certain biochemical parameters such as total lipids, total cholesterol, high and low density lipoproteins, the ratio of high density lipoprotein / total cholesterol (TC) and triglycerides in plasma were determined. The results showed that the adding of flaxseed oil to rat's diet lowers plasma cholesterol, triglycerides, and LDL while the adding of evening primrose in the rat's diet significantly lowers cholesterol and triglycerides. The group of rats fed on both oils cause an increase in HDL and HDL/TC ratio. No significant effect (p<0.05) using both oils was observed on the nutritional evaluation. These data indicate that n-3 and n-6 fatty acids found in flaxseed oil and evening primrose oil respectively, participate in the plasma lipids metabolism of rats. The present study examines the effect of using small amount of flaxseed and evening primrose oils (8 %) for the therapy of hyper-lipidemia.
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