Assessment of 3-Monochloro 1, 2-Propanediol in some Egyptian Foods and Its Impact on Liver and Renal Toxicity in Rats تقدير 3- أحادى کلور بروبان 2،1 داى ول فى بعض الاغذية المصرية وتأثيرة على سمية الکبد والکلى فى الجرذان

Document Type : Original Article

Authors

1 Biochemistry Department, Faculty of Agriculture, Benha University, Benha 13736, Egypt

2 Biochemistry Department, Faculty of Agriculture, Benha University, Benha 13736, Egypt.

3 Department of Industrial Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City 22857/79, Egypt.

4 Biochemistry department,Faculty of agriculture, Benha university

Abstract

This study reports the results of the survey study on 3-monochloro1,2-propanediol (3-MCPD) levels in selected foods, oils and fats collected from supermarkets and restaurants in Egypt. Also; study the effect of feeding of rat on diet contained palm oil rich 3-MCPD on the biochemical parameters of rats. Twenty samples were collected from different supermarkets and restaurants in Egypt to determine 3-MCPD by GC-MS. The oil samples remained after  from falafel  frying showed the highest contents of 3-MCPD esters, with a mean value of 8.20 μg/kg oil, followed by palm oils and oils mixture. Forty Albino rats divided into five groups including one as a basal diet control. The other groups were fed on a a basal diet and replaced corn oil with crude palm oil heated at 200°C for 30min, heated palm oil at 200°C for 6h and palm oil fried with tortilla chips. Rats fed on either heated palm oil at 200°C for 6h and  fried palm oil with tortilla chips showed elevated liver and kidney functions as well as lipid profile except HDL-cholesterol and damages in some histological liver and kidney tissue compared with the control basal diet.This would risk forming esters of 3-MCPD fatty acids. 

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